Description

Prothipendyl is a potent and versatile pharmaceutical intermediate belonging to the phenothiazine class of compounds. This high-purity substance is critical for the research and development of neuropharmacological agents, particularly those targeting the central nervous system. It is an essential building block for pharmaceutical manufacturers and advanced research institutions engaged in the synthesis of novel therapeutic compounds. Prothipendyl CAS NO 303-69-5 is supplied under stringent quality control to ensure batch-to-batch consistency for demanding applications.

Application

• Primary intermediate in the synthesis of antipsychotic and neuroleptic pharmaceutical agents.
• Key starting material for research into dopamine receptor antagonists.
• Used in the development of sedative and antiemetic medications.
• Critical component in preclinical and pharmacological studies for central nervous system disorders.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Building block for the synthesis of more complex phenothiazine derivatives with tailored biological activity.

Basic Information

Product Name	Prothipendyl
CAS No.	303-69-5
Molecular Formula	C₁₆H₁₉N₃S
Molecular Weight	285.41 g/mol
Synonyms	Prothipendyl Hydrochloride (common salt form); N,N-Dimethyl-10H-pyrido[3,2-b][1,4]benzothiazine-10-propanamine; Dominal; Tolnate; Azaphenothiazine; NSC 75755; 10-[3-(Dimethylamino)propyl]-10H-pyrido[3,2-b][1,4]benzothiazine
EINECS	206-150-6

Quality Control

Our Prothipendyl is manufactured under a strict quality management system. Every batch is subjected to comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.