Description

Hydroxydione CAS NO 303-01-5 is a synthetic corticosteroid derivative with significant biological activity. This compound is valued for its potent anti-inflammatory and immunosuppressive properties, making it a key intermediate in advanced pharmaceutical research and development. It is primarily utilized by pharmaceutical manufacturers and research institutions focused on developing novel therapeutic agents for inflammatory and autoimmune conditions.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of more complex corticosteroid drugs.
• Biochemical Research: Used in laboratory studies to investigate glucocorticoid receptor mechanisms and signaling pathways.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Anti-inflammatory Agent Development: Acts as a lead compound for the research and development of new topical or systemic anti-inflammatory medications.

Basic Information

Product Name	Hydroxydione
CAS No.	303-01-5
Molecular Formula	C₂₁H₂₈O₅
Molecular Weight	360.44 g/mol
Synonyms	11β,21-Dihydroxypregn-4-ene-3,20-dione; 11β-Hydroxydione; 11β,21-Dihydroxyprogesterone; 11β-Hydroxy-21-deoxycorticosterone; 11β-Hydroxy-21-desoxycorticosterone; 11β-Hydroxypregn-4-ene-3,20-dione; 11β,21-Dihydroxy-4-pregnene-3,20-dione
EINECS	206-138-5

Quality Control

Our Hydroxydione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.