Description

Dimethyltubocurarine is a semi-synthetic derivative of the natural alkaloid tubocurarine, functioning as a potent non-depolarizing neuromuscular blocking agent. This compound is critical for research and development in pharmacology and anesthesiology, where precise control of neuromuscular transmission is required. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of fine chemicals for neurological studies and as a reference standard.

Application

• Pharmacological Research: As a key tool compound for studying neuromuscular junction physiology and the mechanisms of non-depolarizing muscle relaxants.
• Anesthesia & Surgery Studies: Used in preclinical research to model and investigate neuromuscular blockade and its reversal.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical manufacturing and regulatory testing.
• Neuroscience Investigations: Employed in electrophysiological studies to understand synaptic transmission and receptor antagonism at nicotinic acetylcholine receptors.
• Fine Chemical Synthesis: Acts as a sophisticated intermediate or precursor in the synthesis of more complex neuromuscular agents or labeled derivatives.

Basic Information

Product Name	Dimethyltubocurarine
CAS No.	35-67-6
Molecular Formula	C40H48N2O62+ • 2X-
Molecular Weight	652.82 g/mol (for free base, C40H48N2O6)
Synonyms	Dimethyl Tubocurarine; Dimethyl-D-tubocurarine; Metocurine (common name); Metocurine Iodide (salt form); Dimethylcurine; N,N-Dimethyltubocurarine; (+)-Tubocurarine Dimethyl Ether; Chondodendrum tomentosum extract derivative
EINECS	Contact for details

Quality Control

Our Dimethyltubocurarine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.