Description

Fmoc-L-Lys[C20-Otbu-Glu(Otbu)-Aeea-Aeea]-Oh is a sophisticated, multi-functional building block designed for advanced peptide synthesis and bioconjugation. This compound is engineered to provide researchers and manufacturers with a versatile linker system for creating complex, site-specifically modified biomolecules. It is essential for professionals in pharmaceutical R&D, biotech, and diagnostic reagent development who require high-purity intermediates for antibody-drug conjugates (ADCs), peptide therapeutics, and targeted delivery systems.

Application

• Antibody-Drug Conjugate (ADC) Linker-Payload Construction: Serves as a critical component for attaching cytotoxic drugs to monoclonal antibodies via cleavable or non-cleavable linker systems.
• Peptide & Protein Modification: Used to introduce functional handles (e.g., for click chemistry, fluorophore attachment) into synthetic peptides and recombinant proteins.
• Solid-Phase Peptide Synthesis (SPPS): Acts as a specialized Fmoc-protected amino acid derivative for the controlled assembly of complex peptide sequences with branched architectures.
• Prodrug Development: Facilitates the design of peptide-based prodrugs by enabling the attachment of masking groups or targeting moieties.
• Diagnostic Probe Synthesis: Enables the creation of targeted imaging agents for in vitro and in vivo diagnostics.
• Biomaterial Functionalization: Used to modify surfaces or polymer scaffolds with bioactive peptide sequences to enhance cell adhesion and tissue engineering applications.

Basic Information

Product Name	Fmoc-L-Lys[C20-Otbu-Glu(Otbu)-Aeea-Aeea]-Oh
CAS No.	2915356-76-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fmoc-Lys(C20-Glu(Otbu)-Aeea-Aeea)-OH; Fmoc-L-Lysine(C20-O-tert-butyl-L-glutamate-O-tert-butyl-2-[2-(2-aminoethoxy)ethoxy]acetamide-2-[2-(2-aminoethoxy)ethoxy]acetamide); Fmoc-Lys(PEG2-Glu(Otbu)-PEG2)-OH; Nα-Fmoc-Nε-[(20-carboxy-15-oxo-4,7,10,13-tetraoxa-16-azaicosan-1-oyl)-γ-O-tert-butyl-L-α-glutamyl]-L-lysine; Fmoc-Lys(Ado)-OH (branched linker variant); Fmoc-protected branched PEG linker amino acid
EINECS	Contact for details

Quality Control

Our Fmoc-L-Lys[C20-Otbu-Glu(Otbu)-Aeea-Aeea]-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency for critical research and development. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, MS for identity confirmation, and NMR for structural verification. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms
Purity (HPLC)	≥95.0%
Water Content (KF)	≤2.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.