Description

Tryptophan, 2-Hydroxy-, Hydrochloride (1:1) is a specialized derivative of the essential amino acid tryptophan, modified with a hydroxyl group and presented as a hydrochloride salt for enhanced stability and solubility. This compound is of significant interest for advanced research and development in pharmaceutical chemistry and biochemistry. It serves as a critical building block for scientists and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly for investigating novel metabolic pathways and developing high-value active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Peptide Synthesis: Serves as a modified amino acid building block in solid-phase and solution-phase peptide synthesis for creating peptides with unique properties.
• Nutritional Science Studies: Employed in research to study the metabolism and function of hydroxylated tryptophan derivatives in vitro.
• Reference Standard: Utilized as a high-purity analytical standard in HPLC, LC-MS, and NMR for quality control and method development.
• Fine Chemical Production: Acts as a starting material for the manufacture of more complex chiral molecules and specialty chemicals.

Basic Information

Product Name	Tryptophan, 2-Hydroxy-, Hydrochloride (1:1)
CAS No.	2822463-47-6
Molecular Formula	C₁₁H₁₃N₂O₃·HCl
Molecular Weight	272.69 g/mol (monoisotopic)
Synonyms	2-Hydroxytryptophan Hydrochloride; 2-OH-Trp HCl; (2S)-2-Amino-3-(2-hydroxy-1H-indol-3-yl)propanoic acid hydrochloride; α-Amino-1H-indole-3-propanoic acid, 2-hydroxy-, hydrochloride, L-; L-2-Hydroxytryptophan HCl; 5-Hydroxy-DL-tryptophan hydrochloride (isomer); 6-Hydroxytryptophan hydrochloride (isomer); Tryptophan hydroxylated derivative HCl
EINECS	Contact for details

Quality Control

Our Tryptophan, 2-Hydroxy-, Hydrochloride (1:1) is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.