Description

4H-Pyrrolo[3,2-D]Pyrimidin-4-One, 3,5-Dihydro-2-[[(3R,5R)-1-Methyl-5-[4-(Phenylmethoxy)Phenyl]-3-Piperidinyl]Amino]-3-(2-Propen-1-Yl)- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for its potential role as a key building block in novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel small-molecule drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities with targeted biological activity.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for potential API manufacturing.
• Biochemical Research: May be utilized as a tool compound or a precursor for probes in biochemical and pharmacological assays to study specific biological pathways.
• Custom Synthesis: A starting material for the contract synthesis of specialized, high-value compounds for preclinical and clinical studies.

Basic Information

Product Name	4H-Pyrrolo[3,2-D]Pyrimidin-4-One, 3,5-Dihydro-2-[[(3R,5R)-1-Methyl-5-[4-(Phenylmethoxy)Phenyl]-3-Piperidinyl]Amino]-3-(2-Propen-1-Yl)-
CAS No.	2755823-12-0
Molecular Formula	C28H32N6O2
Molecular Weight	484.59 g/mol
Synonyms	3,5-Dihydro-2-[[(3R,5R)-1-methyl-5-[4-(phenylmethoxy)phenyl]-3-piperidinyl]amino]-3-(2-propen-1-yl)-4H-pyrrolo[3,2-d]pyrimidin-4-one; (3R,5R)-1-Methyl-5-(4-(benzyloxy)phenyl)-N-(3-(prop-2-en-1-yl)-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-2-yl)piperidin-3-amine; CAS 2755823-12-0; 4H-Pyrrolo[3,2-d]pyrimidin-4-one derivative; Advanced pyrrolopyrimidine intermediate.
EINECS	Contact for details

Quality Control

This high-value intermediate is produced under strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical quality attributes. Our commitment to cGMP-compliant practices ensures the material is suitable for use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.