Description

Pyrimidine, 2-(Difluoromethoxy)-4,-Methyl- is a specialized fluorinated pyrimidine derivative, a key building block in advanced organic synthesis. This compound matters for its unique difluoromethoxy moiety, which can significantly alter the physicochemical and metabolic properties of target molecules, enhancing their stability and bioavailability. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoromethoxy group can improve efficacy and environmental profile.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and advanced materials with specific optical or electronic properties.
• Chemical Synthesis: A versatile fluorinating reagent and building block for introducing the -OCF2H group into complex molecular architectures in medicinal and process chemistry.
• Life Science Research: Employed as a biochemical tool and probe in academic and industrial research to study enzyme interactions and metabolic pathways.

Basic Information

Item	Details
Product Name	Pyrimidine, 2-(Difluoromethoxy)-4,-Methyl-
CAS No.	2703752-84-3
Molecular Formula	C6H6F2N2O
Molecular Weight	160.12 g/mol
Synonyms	2-(Difluoromethoxy)-4-methylpyrimidine; 4-Methyl-2-(difluoromethoxy)pyrimidine; 2-Difluoromethoxy-4-methylpyrimidine; 4-Methylpyrimidine, 2-(difluoromethoxy)-; 2703752-84-3 (CAS); DFMP (abbreviation)
EINECS	Contact for details

Quality Control

Our Pyrimidine, 2-(Difluoromethoxy)-4,-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and other fluorides. For long-term storage, consider using an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.