Description

4-(6,7-Dimethoxyquinazolin-4-Yl)-1,4-Diazepane-1-Sulfonamide Hydrochloride is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is critical for medicinal chemists exploring novel therapeutic agents, particularly in kinase inhibitor discovery. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of targeted kinase inhibitors for oncology and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Assay Development: Serves as a reference standard or active compound in high-throughput screening and enzyme inhibition assays.
• Preclinical Drug Development: Employed in the production of compounds for pharmacological and toxicological evaluation.
• Academic Research: Utilized in university and institutional labs for chemical biology and drug discovery projects.
• Custom Synthesis: Starting material for the contract manufacturing of specialized APIs and novel chemical entities.

Basic Information

Product Name	4-(6,7-Dimethoxyquinazolin-4-Yl)-1,4-Diazepane-1-Sulfonamide Hydrochloride
CAS No.	2687222-59-7
Molecular Formula	C₁₇H₂₄ClN₅O₄S
Molecular Weight	429.92 g/mol
Synonyms	1,4-Diazepane-1-sulfonamide, 4-(6,7-dimethoxy-4-quinazolinyl)-, hydrochloride (1:1); 4-(6,7-Dimethoxyquinazolin-4-yl)-1,4-diazepane-1-sulfonamide HCl; 4-(6,7-Dimethoxy-4-quinazolinyl)-1,4-diazepane-1-sulfonamide hydrochloride; 2687222-59-7; UNII-9H6K8F8Q4F; 9H6K8F8Q4F; 4-(6,7-dimethoxyquinazolin-4-yl)-1,4-diazepane-1-sulfonamide monohydrochloride
EINECS	Contact for details

Quality Control

Our 4-(6,7-Dimethoxyquinazolin-4-Yl)-1,4-Diazepane-1-Sulfonamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.