Description

2-Amino-2-(2-Fluorophenyl)Propan-1-Ol Hydrochloride is a high-purity, fluorinated amino alcohol hydrochloride salt, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a structurally defined scaffold with a fluorine atom, which is essential for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and psychiatric drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel psychoactive substances, antidepressants, and neuroleptic agents.
• Advanced Organic Synthesis: Used as a versatile building block for constructing complex, fluorinated molecular architectures in medicinal chemistry.
• Active Pharmaceutical Ingredient (API) Development: Integral to research programs aiming to incorporate fluorine for improved drug potency and pharmacokinetic profiles.
• Chemical Biology & Proteomics: Employed in the design and synthesis of fluorinated probes and molecular tools for studying biological systems.
• Process Chemistry & Scale-up: Serves as a starting material or intermediate in the development of scalable, GMP-compliant synthetic routes for clinical candidates.

Basic Information

Item	Detail
Product Name	2-Amino-2-(2-Fluorophenyl)Propan-1-Ol Hydrochloride
CAS No.	2665661-13-0
Molecular Formula	C9H13ClFNO
Molecular Weight	205.66 g/mol
Synonyms	2-Amino-2-(2-fluorophenyl)propan-1-ol HCl; 1-Propanol, 2-amino-2-(2-fluorophenyl)-, hydrochloride; (RS)-2-Amino-2-(2-fluorophenyl)propan-1-ol hydrochloride; 2-Fluoro-α-(aminomethyl)benzyl alcohol hydrochloride; α-(Aminomethyl)-2-fluorobenzyl alcohol hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-2-(2-Fluorophenyl)Propan-1-Ol Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC/GC purity, chiral purity, and identity confirmation (IR, NMR). A detailed Certificate of Analysis (COA) is provided with each shipment, and we support customer audits and regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.