Description

L-Serine, o-Cyclobutyl-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- is a specialized, high-purity amino acid derivative designed for advanced research and pharmaceutical development. This compound is a protected serine analog, where the Fmoc (9-fluorenylmethoxycarbonyl) group provides a crucial orthogonal protecting strategy for peptide synthesis. It is essential for researchers and manufacturers requiring precise building blocks for the synthesis of complex peptides, peptidomimetics, and novel therapeutic agents. The product, with CAS number 2642331-49-3, serves critical roles in medicinal chemistry, biochemistry, and process development for next-generation pharmaceuticals.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected amino acid, it serves as a key monomer for the controlled, sequential assembly of custom peptides.
• Medicinal Chemistry & Drug Discovery: Used in the research and development of novel peptide-based drugs, enzyme inhibitors, and receptor ligands.
• Bioconjugation & Probe Development: Acts as a versatile intermediate for creating labeled peptides, imaging agents, and affinity probes for biological studies.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Biochemical Research: Utilized in studies of protein structure-function relationships, enzyme mechanisms, and metabolic pathways.
• Combinatorial Chemistry: A valuable building block for generating diverse chemical libraries for high-throughput screening.

Basic Information

Product Name	L-Serine, o-Cyclobutyl-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-
CAS No.	2642331-49-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fmoc-Ser(Cyclobutyl)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-cyclobutyl-L-serine; Fmoc-O-cyclobutyl-L-serine; O-Cyclobutyl-N-Fmoc-L-serine; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-(cyclobutyloxy)propanoic acid; Fmoc-L-Ser(O-Cyclobutyl)-OH; Protected L-Serine Derivative; Peptide Synthesis Building Block
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing all test results are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability and purity. Keep container tightly sealed in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.