Description

L-Serine, o-Cyclopropyl-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- is a sophisticated, high-purity amino acid derivative designed for advanced research and pharmaceutical development. This compound serves as a critical protected serine building block in solid-phase peptide synthesis (SPPS), enabling the precise construction of complex peptides and proteins. It is essential for researchers and manufacturers in pharmaceutical R&D, biotechnology, and fine chemical synthesis who require reliable, high-quality intermediates for developing novel therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected serine derivative for the automated synthesis of peptides and small proteins.
• Pharmaceutical Intermediate: Used in the research and development of peptide-based drugs, including hormones, antibiotics, and enzyme inhibitors.
• Bioconjugation & Labeling: Serves as a modified amino acid for introducing specific functional groups or labels into biomolecules.
• Chemical Biology Research: Employed in studying protein structure-function relationships, enzyme mechanisms, and molecular recognition.
• Fine Chemical Synthesis: Acts as a chiral synthon for the asymmetric synthesis of more complex organic molecules and natural product analogs.
• Protecting Group Chemistry: Utilized in multi-step organic syntheses where selective protection and deprotection of the serine side chain are required.

Basic Information

Product Name	L-Serine, o-Cyclopropyl-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-
CAS No.	2642331-45-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fmoc-Ser(cyclopropyl-OH)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-cyclopropyl-L-serine; Fmoc-O-cyclopropyl-L-serine; Fmoc-L-Ser(O-cPr)-OH; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3-(cyclopropyloxy)propanoic acid; Protected L-Serine derivative; Amino acid building block for SPPS
EINECS	Contact for details

Quality Control

Our Fmoc-protected amino acid derivatives are manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive pharmaceutical applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry best practices and can provide materials that align with cGMP guidelines for advanced research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.