Description

3-Pyridinebutanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Methylamino]-, (αs)- is a specialized, high-purity Fmoc-protected amino acid derivative designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise control over peptide chain assembly, particularly in the development of novel therapeutic agents and biochemical tools. Its primary value lies in enabling the synthesis of complex peptides with specific stereochemistry and functional groups. This product is essential for pharmaceutical R&D, biotechnology, and academic laboratories focused on peptide-based drug discovery and proteomics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the automated, stepwise assembly of custom peptide sequences in drug discovery.
• Pharmaceutical Intermediate: Used in the research and development of peptide-based active pharmaceutical ingredients (APIs) and therapeutic candidates.
• Bioconjugation: Facilitates the site-specific labeling or modification of peptides and proteins for diagnostic and research applications.
• Combinatorial Chemistry: Serves as a valuable reagent in libraries for high-throughput screening to identify new bioactive compounds.
• Academic & Institutional Research: Supports fundamental studies in biochemistry, medicinal chemistry, and molecular biology involving peptide structure and function.
• Production of Custom Peptides: Used by CROs and CDMOs for the contract manufacturing of specific peptide sequences for clients.

Basic Information

Product Name	3-Pyridinebutanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Methylamino]-, (αs)-
CAS No.	2642331-40-4
Molecular Formula	C25H24N2O4
Molecular Weight	416.47 g/mol
Synonyms	Fmoc-3-(2-Pyridyl)-D-alanine; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(pyridin-2-yl)propanoic acid; Fmoc-D-2-Pyridylalanine(N-Me); N-Methyl-Fmoc-3-(2-pyridyl)-D-alanine; N-Me-Fmoc-3-(2-Pyridyl)-D-Ala-OH; α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]methylamino]-3-pyridinepropanoic acid, (αS)-; Fmoc-N-Me-2-Pyridyl-D-Ala-OH
EINECS	Contact for details

Quality Control

Our 3-Pyridinebutanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Methylamino]-, (αs)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We support compliance needs for cGMP and other relevant regulatory frameworks upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.