Description

4-(Dimethylphosphoryl)Pyrimidin-2-Amine is a high-purity, organophosphorus-substituted pyrimidine derivative, serving as a critical building block in advanced chemical synthesis. Its unique phosphoryl-amine functionalization on the pyrimidine ring makes it a valuable intermediate for developing novel active compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating targeted molecules with specific biological activities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel kinase inhibitors, antiviral agents, and other small-molecule drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage its phosphoryl moiety.
• Ligand Synthesis: Serves as a sophisticated ligand or ligand precursor in coordination chemistry and catalysis.
• Material Science: Building block for creating functionalized polymers or organic electronic materials with tailored properties.
• Chemical Biology: Probe or linker molecule for studying biochemical pathways and protein interactions.
• Custom Synthesis: Foundation for contract research organizations (CROs) and fine chemical manufacturers to produce bespoke compounds for clients.

Basic Information

Product Name	4-(Dimethylphosphoryl)Pyrimidin-2-Amine
CAS No.	2639424-58-9
Molecular Formula	C6H10N3OP
Molecular Weight	171.14 g/mol
Synonyms	2-Amino-4-(dimethylphosphoryl)pyrimidine; 4-(Dimethylphosphoryl)-2-pyrimidinamine; 4-(Dimethylphosphinyl)pyrimidin-2-amine; 4-(Dimethylphosphoryl)-2-aminopyrimidine; 2-Pyrimidinamine, 4-(dimethylphosphoryl)-; 4-(N,N-Dimethylphosphoramidyl)pyrimidin-2-amine; 4-(Dimethylphosphonamido)pyrimidin-2-amine
EINECS	Contact for details

Quality Control

Every batch of 4-(Dimethylphosphoryl)Pyrimidin-2-Amine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.