Description

Glycine, n-2-Butyn-1-Yl-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- CAS NO 2639419-13-7 is a specialized, high-purity Fmoc-protected amino acid derivative designed for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular construction, particularly in the development of novel peptides and bioactive molecules. It serves as a key building block for pharmaceutical R&D, proteomics, and the synthesis of complex chemical libraries where controlled reactivity and high fidelity are paramount.

Application

• Solid-Phase Peptide Synthesis (SPPS): A crucial protected amino acid derivative for the sequential assembly of peptides using Fmoc chemistry protocols.
• Pharmaceutical Research & Development: Used as a key intermediate in the synthesis of novel drug candidates, peptide therapeutics, and targeted biologics.
• Combinatorial Chemistry: Serves as a building block for generating diverse chemical libraries for high-throughput screening and drug discovery.
• Bioconjugation: Facilitates the site-specific modification of proteins, antibodies, and other biomolecules due to its reactive alkyne functionality.
• Proteomics and Chemical Biology: Employed in the study of protein-protein interactions and the development of activity-based probes.
• Agrochemical Research: Used in the synthesis of novel peptide-based crop protection agents and bioactive compounds.

Basic Information

Product Name	Glycine, n-2-Butyn-1-Yl-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-
CAS No.	2639419-13-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fmoc-Glycine-2-butynyl ester; N-(2-Butyn-1-yl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycine; N-Fmoc-N-(2-butynyl)glycine; Fmoc-Gly(2-butynyl)-OH; Glycine, N-(2-butynyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-; Fmoc-protected propargylglycine derivative; Amino acid alkyne building block
EINECS	Contact for details

Quality Control

This high-value synthetic intermediate is produced under strict quality control in a GMP-compliant environment. Every batch is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. This material is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to prevent condensation. Store in a cool, dry, well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.