Description

(S)-4-Isopropyl-2-(Pyrimidin-2-Yl)-4,5-Dihydrooxazole CAS NO 2634687-59-3 is a high-purity, chiral oxazoline derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile ligand precursor and chiral auxiliary, enabling the production of enantiomerically pure compounds for demanding applications. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in asymmetric catalysis.
• Catalyst Ligand Precursor: Used to synthesize sophisticated chiral ligands for transition metal catalysis in fine chemical manufacturing.
• Agrochemical Research: Building block for creating novel, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Asymmetric Synthesis: Employed as a chiral auxiliary or controller in stereoselective carbon-carbon and carbon-heteroatom bond-forming reactions.
• Material Science: Potential monomer or additive for developing chiral polymers and advanced functional materials.
• Academic & Contract Research: Vital reagent for methodological development in organic chemistry and process research at universities and CROs.

Basic Information

Product Name	(S)-4-Isopropyl-2-(Pyrimidin-2-Yl)-4,5-Dihydrooxazole
CAS No.	2634687-59-3
Molecular Formula	C10H13N3O
Molecular Weight	191.23 g/mol
Synonyms	(S)-4-(Propan-2-yl)-2-(pyrimidin-2-yl)-4,5-dihydro-1,3-oxazole; (S)-4-Isopropyl-2-(pyrimidin-2-yl)-2-oxazoline; (S)-2-(2-Pyrimidinyl)-4-isopropyl-4,5-dihydrooxazole; (S)-ValPyOx; (S)-iPr-PyOx; Chiral Pyrimidyl Oxazoline Ligand Precursor; (S)-Enantiomer of 4,5-Dihydro-4-(1-methylethyl)-2-(2-pyrimidinyl)oxazole
EINECS	Contact for details

Quality Control

Every batch of (S)-4-Isopropyl-2-(Pyrimidin-2-Yl)-4,5-Dihydrooxazole is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric excess (ee) and chemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided with each shipment to guarantee reliable and consistent performance in your processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.