Description

(S)-1-(3-Fluoro-4-Methylphenyl)Ethan-1-Amine, Hcl is a high-purity chiral amine building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals, where its specific stereochemistry is paramount for biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for creating novel, targeted molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereoisomers exhibit enhanced efficacy.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process optimization.

Basic Information

Product Name	(S)-1-(3-Fluoro-4-Methylphenyl)Ethan-1-Amine, Hcl
CAS No.	2633683-38-0
Molecular Formula	C9H13ClFN
Molecular Weight	189.66 g/mol
Synonyms	(S)-1-(3-Fluoro-4-methylphenyl)ethanamine hydrochloride; (S)-α-Methyl-3-fluoro-4-methylbenzylamine hydrochloride; (1S)-1-(3-Fluoro-4-methylphenyl)ethan-1-amine hydrochloride; (S)-3-Fluoro-4-methylamphetamine HCl; (S)-1-(3-Fluoro-p-tolyl)ethylamine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of (S)-1-(3-Fluoro-4-Methylphenyl)Ethan-1-Amine, Hcl is produced under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are manufactured to meet the stringent requirements for advanced pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% e.e.
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.