Description

4-Pentenoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Methylamino]-, (2S)- is a specialized, optically active Fmoc-protected amino acid derivative designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring high-purity, chiral building blocks to construct complex biomolecules with precise stereochemistry. It is primarily utilized in pharmaceutical R&D, particularly in the development of peptide-based therapeutics, diagnostics, and as a key intermediate in solid-phase peptide synthesis (SPPS).

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Solid-Phase Peptide Synthesis (SPPS): Used as a protected amino acid derivative for the controlled, sequential assembly of peptides on resin supports.
• Bioconjugation & Probe Development: Enables the site-specific incorporation of functional handles or labels into peptides for diagnostic and research applications.
• Chemical Biology Research: Employed in studying protein-protein interactions, enzyme mechanisms, and for creating peptide libraries.
• Agrochemical Research: Serves as a precursor for developing bioactive peptides with potential applications in crop protection.

Basic Information

Product Name	4-Pentenoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Methylamino]-, (2S)-
CAS No.	2606012-88-6
Molecular Formula	C22H23NO5
Molecular Weight	381.42 g/mol
Synonyms	(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)pent-4-enoic acid; Fmoc-N-Me-δPren-OH; Fmoc-N-methyl-2-amino-4-pentenoic acid; Fmoc-N-methyl-δPren-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-2-amino-4-pentenoic acid; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-4-pentenoic acid; Fmoc-N-Me-δPren
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure exceptional chiral purity and chemical identity. Certificates of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH Q7 guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.