Description

1-Pyrrolidinepentanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-δ-Oxo-, (αs)- is a high-purity, non-natural amino acid derivative featuring a protected α-amino group via the 9-fluorenylmethoxycarbonyl (Fmoc) moiety. This compound is of critical importance as a specialized building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptide sequences. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected amino acid derivative for the automated, sequential construction of custom peptides.
• Pharmaceutical R&D: Used in the research and development of novel peptide-based drugs, including hormone analogs and enzyme inhibitors.
• Bioconjugation: Acts as a precursor for creating peptide tags or linkers for protein labeling and bioconjugation strategies.
• Chemical Biology: Employed in the synthesis of peptide libraries for high-throughput screening against biological targets.
• Academic Research: Utilized in university and institutional labs for fundamental studies in peptide chemistry and structure-activity relationships (SAR).
• Production of Peptidomimetics: Provides a scaffold for the development of metabolically stable peptide mimics with enhanced drug-like properties.

Basic Information

Product Name	1-Pyrrolidinepentanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-δ-Oxo-, (αs)-
CAS No.	2559759-52-1
Molecular Formula	C24H26N2O5
Molecular Weight	422.48 g/mol
Synonyms	Fmoc-δ-Oxo-norvaline-OH; Fmoc-dehydro-norvaline; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)pent-4-enoic acid; α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-δ-oxo-1-pyrrolidinepentanoic acid; Fmoc-DhNva-OH; Fmoc-(S)-2-amino-4-pentenoic acid; N-α-Fmoc-dehydronorvaline
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized to confirm identity, purity, and consistency, with a typical HPLC purity specification of ≥95% (Area %). Certificates of Analysis (COA) detailing specific batch results are available upon request. We adhere to a quality management system suitable for supplying materials for research and development under cGMP-like controls where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.