Description

β-Alanine, n-[3-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl)-1-Oxopropyl]-, 2,5-Dioxo-1-Pyrrolidinyl Ester CAS NO 2512227-14-2 is a specialized organic compound featuring both β-alanine and maleimide-derived functional groups. This molecular architecture makes it a valuable versatile linker and building block for advanced chemical synthesis, particularly in the creation of functionalized polymers and bioconjugates. It is essential for R&D and production teams in the pharmaceutical, biotech, and advanced materials sectors seeking to develop novel drug delivery systems, diagnostic agents, or specialty polymers.

Application

• Bioconjugation and Protein Modification: The maleimide moiety enables selective thiol coupling, making it a key reagent for attaching peptides, drugs, or labels to antibodies, proteins, and other biomolecules.
• Polymer Chemistry & Functional Materials: Serves as a monomer or cross-linking agent for synthesizing smart hydrogels, responsive polymers, and coatings with tailored properties.
• Pharmaceutical Intermediate: Used in the research and development of prodrugs and targeted therapeutics, especially in antibody-drug conjugates (ADCs) and other targeted delivery platforms.
• Diagnostic Reagent Synthesis: Employed in the fabrication of contrast agents, fluorescent probes, and other diagnostic tools for medical imaging and assays.
• Surface Functionalization: Applied to modify nanoparticles, chips, or other surfaces to introduce specific chemical handles for further immobilization or reaction.
• Research & Development: A critical tool in academic and industrial labs for exploring new synthetic pathways and creating novel chemical entities with specific functionalities.

Basic Information

Item	Detail
Product Name	β-Alanine, n-[3-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl)-1-Oxopropyl]-, 2,5-Dioxo-1-Pyrrolidinyl Ester
CAS No.	2512227-14-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-(3-(2,5-Dioxopyrrolidin-1-yl)-3-oxopropyl)-1H-pyrrole-2,5-dione; Maleimide-PEG2-OSu; β-Alanine, N-[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]-, 2,5-dioxo-1-pyrrolidinyl ester; NHS-PEG2-Maleimide; Maleimide-PEG2-NHS ester; Succinimidyl ester of maleimide-PEG2-β-alanine; N-(3-Maleimidopropionyloxy)succinimide; A heterobifunctional crosslinker with NHS ester and maleimide groups.
EINECS	Contact for details

Quality Control

Our β-Alanine, n-[3-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl)-1-Oxopropyl]-, 2,5-Dioxo-1-Pyrrolidinyl Ester is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive applications like bioconjugation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical R&D and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under anhydrous conditions and away from direct light to maintain stability and prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.