Description

Pyrido[4,3-D]Pyrimidin-4(3H)-One, 7-Chloro-8-Fluoro- is a high-value pharmaceutical intermediate and research chemical belonging to the pyridopyrimidine class of heterocyclic compounds. Its core value lies in its role as a key building block for the synthesis of novel, biologically active molecules, particularly in drug discovery pipelines. This compound is essential for research and development teams in the pharmaceutical and biotechnology sectors focused on creating new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Kinase Inhibitor Research: Serves as a core scaffold for the development of novel kinase inhibitors, a major class of drugs for oncology and inflammatory diseases.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of drug candidates.
• Biochemical Research: Employed as a tool compound in enzymatic assays and biological screening to study specific protein targets.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects for clients.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic chemistry and drug discovery methodologies.

Basic Information

Product Name	Pyrido[4,3-D]Pyrimidin-4(3H)-One, 7-Chloro-8-Fluoro-
CAS No.	2454396-93-9
Molecular Formula	C7H3ClFN3O
Molecular Weight	199.57 g/mol
Synonyms	7-Chloro-8-fluoropyrido[4,3-d]pyrimidin-4(3H)-one; 7-Chloro-8-fluoro-3,4-dihydropyrido[4,3-d]pyrimidin-4-one; 7-Chloro-8-fluoro-4-hydroxy-pyrido[4,3-d]pyrimidine; 2454396-93-9; 7-Chloro-8-fluoro-4(3H)-pyrido[4,3-d]pyrimidinone
EINECS	Contact for details

Quality Control

Our Pyrido[4,3-D]Pyrimidin-4(3H)-One, 7-Chloro-8-Fluoro- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.