Description

2,4,7-Trichloro-8-Fluoropyrido[4,3-D]Pyrimidine is a high-value, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure is engineered to serve as a versatile intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought after by research institutions and industrial R&D departments focused on developing novel active ingredients, such as kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted drug candidates, especially kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated pyrimidine core for bioactivity.
• Material Science: Serves as a building block for creating specialized organic electronic materials and ligands for catalysis.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis: Provides a key scaffold for contract research organizations (CROs) and fine chemical manufacturers performing bespoke synthesis for clients.

Basic Information

Product Name	2,4,7-Trichloro-8-Fluoropyrido[4,3-D]Pyrimidine
CAS No.	2454396-80-4
Molecular Formula	C7HCl3FN3
Molecular Weight	248.45 g/mol
Synonyms	8-Fluoro-2,4,7-trichloropyrido[4,3-d]pyrimidine; 2,4,7-Trichloro-8-fluoropyrido[4,3-d]pyrimidine; Pyrido[4,3-d]pyrimidine, 2,4,7-trichloro-8-fluoro-; 2454396-80-4; 8-Fluoro-2,4,7-trichloro-1,5-naphthyridine (alternative ring numbering)
EINECS	Contact for details

Quality Control

Every batch of 2,4,7-Trichloro-8-Fluoropyrido[4,3-D]Pyrimidine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Standard Grade)
Purity (HPLC)	≥ 98% (High Purity Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.