Description

Heptanedioic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, 7-(2-Propen-1-Yl) Ester, (2S)- is a sophisticated, high-purity chemical building block designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring precise molecular architecture, particularly in the development of novel active pharmaceutical ingredients (APIs) and complex organic materials. Its primary value lies in its role as a protected, activated intermediate, enabling controlled peptide coupling and polymer synthesis for the pharmaceutical, biotechnology, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key protected amino acid derivative for the solid-phase and solution-phase synthesis of complex peptide-based drugs and prodrugs.
• Bioconjugation Reagent: Used to create stable linkages between biomolecules (e.g., proteins, antibodies) and other functional molecules, such as drugs, dyes, or polymers, for targeted therapies and diagnostics.
• Polymer Chemistry: Serves as a specialized monomer for synthesizing functionalized polyesters and polyamides with tailored properties for biomedical and high-performance material applications.
• Protecting Group Strategy (Fmoc): Utilizes the 9-fluorenylmethoxycarbonyl (Fmoc) protecting group, making it essential for standard Fmoc-based peptide synthesis protocols widely used in research and production.
• Chemical Biology Research: Employed in the design and construction of molecular probes, enzyme inhibitors, and other tools to study biological pathways and mechanisms.
• Custom Synthesis: A starting material for the bespoke synthesis of novel chemical entities (NCEs) and fine chemicals for contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name	Heptanedioic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, 7-(2-Propen-1-Yl) Ester, (2S)-
CAS No.	2413233-46-0
Molecular Formula	C25H27NO6
Molecular Weight	437.49 g/mol
Synonyms	(2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]heptanedioic acid 7-allyl ester; Fmoc-L-2-aminoheptanedioic acid 7-allyl ester; Fmoc-Aad(Alloc)-OH; Nα-Fmoc-L-α-aminopimelic acid γ-allyl ester; Allyl 6-[(S)-2-[(9H-fluoren-9-ylmethoxy)carbonylamino]pentanedioate]; N-Fmoc-L-2-aminoheptanedioic acid 7-allyl ester; Protected L-2-aminopimelic acid derivative; Fmoc-2-Aminoheptanedioic Acid Allyl Ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity suitable for sensitive research and GMP-guided synthesis. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry, to confirm identity, purity, and chiral integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive; allow the sealed container to equilibrate to room temperature before opening to minimize condensation and exposure.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.