Description

Fmoc-D-Met(O)-Oh CAS NO 2410250-48-3 is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring precise chirality and side-chain protection to ensure the correct folding and biological activity of synthetic peptides. It is primarily used by pharmaceutical R&D teams, biotechnology companies, and academic laboratories engaged in developing novel peptide-based therapeutics, diagnostics, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled, sequential assembly of complex peptides.
• Pharmaceutical Research: Synthesis of peptide drug candidates, including antimicrobial peptides and hormone analogs.
• Bioconjugation: Used to introduce methionine sulfoxide-containing motifs for site-specific protein labeling or modification.
• Combinatorial Chemistry: A valuable reagent for generating diverse peptide libraries for screening and drug discovery.
• Biochemical Studies: Synthesis of substrates and inhibitors for enzymatic studies involving oxidation-reduction pathways.
• API Intermediate: Serves as a chiral intermediate in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs).

Basic Information

Item	Details
Product Name	Fmoc-D-Met(O)-Oh
CAS No.	2410250-48-3
Molecular Formula	C₂₀H₂₁NO₅S
Molecular Weight	387.45 g/mol
Synonyms	Fmoc-D-methionine sulfoxide; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-methionine sulfoxide; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(methylsulfinyl)butanoic acid; Fmoc-D-Met(O); Fmoc-D-Methionine S-oxide; N-Fmoc-D-methionine S-oxide; Fmoc-D-Met(O)-OH; D-Methionine sulfoxide, N-Fmoc derivative
EINECS	Contact for details

Quality Control

Every batch of Fmoc-D-Met(O)-Oh is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent in-house specifications for identity, purity, and chiral integrity. A Certificate of Analysis (COA) detailing results for assay, chiral purity, and related substances is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.