Description

4-Pyrimidinecarboxamide, n-(Cyclopropylmethyl)-6-[(3S)-3-Hydroxy-1-Pyrrolidinyl]-2-[(3S)-3-Phenyl-1-Piperidinyl]- is a sophisticated, high-purity pharmaceutical intermediate designed for advanced synthesis. This compound is critical for research and development in medicinal chemistry, offering a complex chiral scaffold for constructing novel therapeutic agents. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing next-generation active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Serves as a critical precursor in the multi-step synthesis of complex, chiral active pharmaceutical ingredients.
• Chemical Biology Probes: Utilized in the development of specialized probes for studying enzyme function and biological target engagement.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	4-Pyrimidinecarboxamide, n-(Cyclopropylmethyl)-6-[(3S)-3-Hydroxy-1-Pyrrolidinyl]-2-[(3S)-3-Phenyl-1-Piperidinyl]-
CAS No.	2393840-15-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-(Cyclopropylmethyl)-6-[(3S)-3-hydroxypyrrolidin-1-yl]-2-[(3S)-3-phenylpiperidin-1-yl]pyrimidine-4-carboxamide; (S)-N-(Cyclopropylmethyl)-6-(3-hydroxypyrrolidin-1-yl)-2-(3-phenylpiperidin-1-yl)pyrimidine-4-carboxamide; 2393840-15-6; UNII-Contact for details; A complex pyrimidinecarboxamide derivative
EINECS	Contact for details

Quality Control

This high-value intermediate is produced under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC for purity and chiral purity verification, to ensure structural integrity and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot, supporting rigorous quality assurance in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Long-term storage under inert atmosphere is recommended.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.