Description

2-Pyrimidinemethanamine, α-Methyl-, Hydrochloride (1:1), (αr)- is a high-purity chiral amine derivative, specifically the hydrochloride salt of an α-methyl-substituted pyrimidine methanamine. This compound is a critical chiral building block and intermediate in advanced pharmaceutical synthesis and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the creation of advanced, targeted pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands in asymmetric catalysis, enabling more efficient and selective chemical transformations.
• Chemical Biology Research: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways and enzyme function.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial production of chiral active pharmaceutical ingredients (APIs).
• Academic Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Pyrimidinemethanamine, α-Methyl-, Hydrochloride (1:1), (αr)-
CAS No.	2387560-79-2
Molecular Formula	C6H10N3Cl
Molecular Weight	159.62 g/mol
Synonyms	(R)-α-Methyl-2-pyrimidinemethanamine hydrochloride; (R)-1-(Pyrimidin-2-yl)ethan-1-amine hydrochloride; (R)-2-(1-Aminoethyl)pyrimidine hydrochloride; (R)-C-1-(Pyrimidin-2-yl)ethylamine hydrochloride; (R)-Amino(2-pyrimidinyl)ethane hydrochloride; (αR)-α-Methyl-2-pyrimidinemethanamine hydrochloride; (R)-2-(1-Aminoethyl)pyrimidine HCl
EINECS	Contact for details

Quality Control

Our 2-Pyrimidinemethanamine, α-Methyl-, Hydrochloride (1:1), (αr)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to prevent degradation. Keep the container tightly sealed in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.