Description

2-Bromo-4-(Difluoromethoxy)Benzaldehyde is a versatile and high-value aromatic aldehyde building block characterized by its bromine and difluoromethoxy substituents. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling the synthesis of advanced materials and active pharmaceutical ingredients. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the difluoromethoxy group can improve metabolic stability and bioavailability.
• Liquid Crystal & OLED Material Development: Serves as a building block for creating advanced organic electronic materials due to its ability to modify molecular polarity and conjugation.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct complex biaryl structures.
• Organic Synthesis & Chemical Research: Employed as a versatile reagent for introducing aldehyde functionality into complex molecules for further derivatization.

Basic Information

Product Name	2-Bromo-4-(Difluoromethoxy)Benzaldehyde
CAS No.	2384658-38-0
Molecular Formula	C8H5BrF2O2
Molecular Weight	251.03 g/mol
Synonyms	4-(Difluoromethoxy)-2-bromobenzaldehyde; 2-Bromo-4-(difluoromethoxy)benzaldehyde; Benzaldehyde, 2-bromo-4-(difluoromethoxy)-; 2-Bromo-4-difluoromethoxybenzaldehyde
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards and precise customer requirements. Each batch is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) documenting all test results are available upon request, providing full traceability and quality assurance for your R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.