Description

Arg-Gly-Asp(Tfa Salt) CAS NO 2378808-45-6 is a high-purity, trifluoroacetic acid (TFA) salt derivative of the Arg-Gly-Asp (RGD) peptide sequence. This compound is a critical intermediate and research tool in the development of targeted therapeutics and diagnostic agents due to its role in modulating integrin receptor interactions. It is primarily utilized by pharmaceutical R&D departments, biotechnology companies, and academic research institutions focused on oncology, cardiovascular disease, and tissue engineering. The product is supplied under stringent quality control to ensure batch-to-batch consistency for sensitive biological applications.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of integrin-targeting drug candidates for cancer therapy and anti-angiogenesis.
• Bioconjugation & Probe Development: For creating fluorescent, radioactive, or affinity-labeled probes to study cell adhesion and signaling pathways.
• Biomaterial & Tissue Engineering: Functionalization of scaffolds and surfaces to promote specific cellular attachment and tissue integration.
• In Vitro Diagnostics (IVD): Component in assay development for screening integrin-ligand interactions and inhibitor efficacy.
• Academic & Basic Research: Tool compound for investigating the role of RGD-integrin binding in various physiological and pathological processes.
• Peptide Library Synthesis: Building block for constructing focused libraries to discover novel bioactive peptides.

Basic Information

Product Name	Arg-Gly-Asp(Tfa Salt)
CAS No.	2378808-45-6
Molecular Formula	C15H25N7O7 • xC2HF3O2
Molecular Weight	Contact for details
Synonyms	RGD TFA Salt; Arg-Gly-Asp trifluoroacetate; H-Arg-Gly-Asp-OH TFA salt; Cyclo(RGDyK) precursor TFA salt; Integrin binding peptide TFA salt; Adhesion peptide derivative; N2-[(phenylmethoxy)carbonyl]-N5-(N-[(phenylmethoxy)carbonyl]glycyl)-L-ornithine TFA; L-Arginylglycyl-L-aspartic acid trifluoroacetate
EINECS	Contact for details

Quality Control

Every batch of Arg-Gly-Asp(Tfa Salt) is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, MS, and NMR, to ensure compliance with research and development grade specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and storage under inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%
Water Content (KF)	≤ 5.0%
TFA Content	10 - 15%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.