Description

7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine, n-Methyl-n-[(3S,4R)-4-Methyl-3-Piperidinyl]- is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted small-molecule therapeutics. It is primarily utilized by pharmaceutical companies, biotechnology research firms, and contract development and manufacturing organizations (CDMOs) engaged in the discovery of novel drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitors and other targeted cancer therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Preclinical Development: Serves as a critical starting material for producing compounds for pharmacological and toxicological evaluation.
• Process Chemistry: Employed in route scouting and scale-up development for active pharmaceutical ingredient (API) manufacturing.
• Biochemical Research: Potential use as a tool compound for probing specific biological pathways and enzyme functions.

Basic Information

Product Name	7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine, n-Methyl-n-[(3S,4R)-4-Methyl-3-Piperidinyl]-
CAS No.	2378663-15-9
Molecular Formula	C13H19N5
Molecular Weight	245.33 g/mol
Synonyms	N-Methyl-N-[(3S,4R)-4-methylpiperidin-3-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine; (3S,4R)-3-[(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino]-4-methylpiperidine; 4-[(3S,4R)-4-Methyl-3-piperidinyl](methyl)amino]-7H-pyrrolo[2,3-d]pyrimidine; CAS 2378663-15-9
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We employ validated analytical methods, including HPLC and NMR, to confirm the specific stereochemistry and chemical integrity critical for your research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.