Description

Pyrido[2,3-D]Pyrimidine-2,7(1H,8H)-Dione, 8-Cyclopentyl-5-Methyl- is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrimidine class of heterocyclic compounds. Its complex molecular architecture makes it a critical building block for the research and development of novel therapeutic agents, particularly in oncology and antiviral fields. This compound is essential for medicinal chemists and process development scientists in pharmaceutical R&D and fine chemical synthesis who require reliable, high-quality intermediates to accelerate their discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of targeted kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Process Chemistry Development: Employed in route scouting and scale-up optimization for the production of active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: Utilized in vitro and in vivo to study specific biological pathways and validate novel drug targets.
• Custom Synthesis & Contract Manufacturing: A vital starting material for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke synthesis services.
• Academic Research: Used in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	Pyrido[2,3-D]Pyrimidine-2,7(1H,8H)-Dione, 8-Cyclopentyl-5-Methyl-
CAS No.	2375089-01-1
Molecular Formula	C13H16N2O2
Molecular Weight	232.28 g/mol
Synonyms	8-Cyclopentyl-5-methyl-1H,8H-pyrido[2,3-d]pyrimidine-2,7-dione; 8-Cyclopentyl-5-methylpyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione; 5-Methyl-8-cyclopentyl-1,8-dihydropyrido[2,3-d]pyrimidine-2,7-dione; 8-Cyclopentyl-5-methyl-1H-pyrido[2,3-d]pyrimidine-2,7-dione; CAS 2375089-01-1
EINECS	Contact for details

Quality Control

Our Pyrido[2,3-D]Pyrimidine-2,7(1H,8H)-Dione, 8-Cyclopentyl-5-Methyl- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.