Description

2-Bromo-4-Chloro-6-Fluoro-3-Methylaniline is a high-purity, multi-halogenated aniline derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and functional agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-infective agents.
• Agrochemical Synthesis: Serves as a core scaffold for developing new-generation herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic structure.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing complex, halogenated azo dyes and high-performance pigments.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) for creating biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for biochemical and diagnostic applications.

Basic Information

Product Name	2-Bromo-4-Chloro-6-Fluoro-3-Methylaniline
CAS No.	2368909-46-8
Molecular Formula	C7H6BrClFN
Molecular Weight	238.49 g/mol
Synonyms	3-Amino-2-bromo-4-chloro-6-fluorotoluene; 2-Bromo-4-chloro-6-fluoro-3-methylbenzenamine; 1-Amino-2-bromo-4-chloro-6-fluoro-3-methylbenzene; Benzenamine, 2-bromo-4-chloro-6-fluoro-3-methyl-; 3-Methyl-2-bromo-4-chloro-6-fluoroaniline; BCFMA; 2368909-46-8
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Chloro-6-Fluoro-3-Methylaniline is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure it meets the highest standards of purity and consistency. Our products are suitable for demanding R&D and scale-up applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles via validated methods such as HPLC, GC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.