Description

2-Bromopyrazolo[1,5-A]Pyrimidin-5(4H)-One is a high-purity brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its versatile reactivity.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and insecticides.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for biological target validation.
• Material Science: Potential precursor for organic electronic materials and functional polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	2-Bromopyrazolo[1,5-A]Pyrimidin-5(4H)-One
CAS No.	2357108-27-9
Molecular Formula	C6H3BrN3O
Molecular Weight	213.01 g/mol
Synonyms	2-Bromopyrazolo[1,5-a]pyrimidin-5(4H)-one; 4H-Pyrazolo[1,5-a]pyrimidin-5-one, 2-bromo-; 2-Bromo-4H-pyrazolo[1,5-a]pyrimidin-5-one; 2-Bromo-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Bromopyrazolo[1,5-A]Pyrimidin-5(4H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.