Description

4-(6,8-Dibromo-3,4-Dihydroquinazolin-3-Yl)-Cyclohexanol Hydrochloride is a high-purity, advanced pharmaceutical intermediate designed for research and development in modern drug discovery. This compound is valued for its unique dibrominated quinazoline scaffold, which is critical for modulating biological activity and pharmacokinetic properties in novel therapeutic candidates. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other enzyme-related pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop compounds with improved efficacy and selectivity.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Biochemical Probe Development: Employed in the creation of chemical probes for investigating biological mechanisms and target validation in cellular assays.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global pharmaceutical development pipelines.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	4-(6,8-Dibromo-3,4-Dihydroquinazolin-3-Yl)-Cyclohexanol Hydrochloride
CAS No.	2356152-56-0
Molecular Formula	C14H17Br2ClN2O
Molecular Weight	424.56 g/mol
Synonyms	4-(6,8-Dibromo-3,4-dihydro-2H-quinazolin-3-yl)cyclohexanol hydrochloride; 4-(6,8-Dibromo-3,4-dihydroquinazolin-3-yl)cyclohexan-1-ol hydrochloride; 4-(6,8-Dibromo-1,2,3,4-tetrahydroquinazolin-3-yl)cyclohexanol HCl; Cyclohexanol, 4-(6,8-dibromo-3,4-dihydro-2H-quinazolin-3-yl)-, hydrochloride; 2356152-56-0; DBQCH-HCl; 6,8-Dibromo-3-(4-hydroxycyclohexyl)-3,4-dihydroquinazoline hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 4-(6,8-Dibromo-3,4-Dihydroquinazolin-3-Yl)-Cyclohexanol Hydrochloride is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.