Description

Benzenebutanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-4-(Phenylmethoxy)-, (αs)- is a high-purity, non-natural amino acid derivative designed for advanced research and pharmaceutical development. This compound serves as a critical building block (Fmoc-protected intermediate) in solid-phase peptide synthesis (SPPS), enabling the precise construction of complex peptide sequences. It is essential for researchers and manufacturers in pharmaceutical R&D, biotechnology, and fine chemical synthesis who require reliable, high-quality intermediates for producing novel therapeutic peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected amino acid derivative, it is a fundamental reagent for the automated, stepwise assembly of custom peptides.
• Pharmaceutical Intermediate: Used in the research and development of novel peptide-based drugs, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Peptidomimetic Design: Incorporates unique structural features (phenylmethoxy side chain) for creating modified peptides with enhanced stability, bioavailability, or receptor affinity.
• Bioconjugation and Labeling: The reactive carboxylic acid group allows for conjugation to other molecules, carriers, or fluorescent tags for diagnostic and research applications.
• Academic and Industrial Research: A key tool in chemical biology and medicinal chemistry for studying protein-protein interactions and developing new bioactive compounds.
• Fine Chemical Synthesis: Serves as a chiral synthon for the asymmetric synthesis of more complex organic molecules beyond peptide chemistry.

Basic Information

Item	Details
Product Name	Benzenebutanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-4-(Phenylmethoxy)-, (αs)-
CAS No.	2350174-95-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fmoc-Asn(OBzl)-OH; Fmoc-L-Asparagine(OBzl)-OH; N-α-Fmoc-N-γ-benzyl-L-asparagine; N-α-(9-Fluorenylmethoxycarbonyl)-N-γ-benzyl-L-asparagine; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-(phenylmethoxy)-4-oxobutanoic acid; Fmoc-Asp(OBzl)-OH (common mis-assignment); Fmoc-Asn(Bzl)-OH; Fmoc-L-Asn(Bzl)-OH
EINECS	Contact for details

Quality Control

Our Benzenebutanoic Acid derivative is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive applications like pharmaceutical R&D. Quality is verified through advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each batch to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (L-Isomer)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.