Description

Fmoc-o-Isopropyl-L-Homoserine is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise control over side-chain functionality and stereochemistry during solid-phase peptide assembly. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and fine chemical suppliers engaged in the development of novel therapeutic peptides, peptidomimetics, and complex biomolecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled incorporation of homoserine analogs with an isopropyl-protected side chain into peptide chains.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Peptidomimetic Design: Enables the creation of modified peptide structures with enhanced metabolic stability, bioavailability, or receptor binding affinity.
• Bioconjugation & Labeling: Serves as a precursor for synthesizing peptide conjugates for diagnostic imaging, drug delivery systems, and biochemical probes.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify new bioactive peptide leads.
• Academic Research: A valuable reagent for studies in organic chemistry, biochemistry, and medicinal chemistry focusing on amino acid and protein engineering.

Basic Information

Product Name	Fmoc-o-Isopropyl-L-Homoserine
CAS No.	2350000-84-7
Molecular Formula	C22H25NO5
Molecular Weight	383.44 g/mol
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(1-methylethyl)-L-homoserine; Fmoc-Homoserine(O-iPr)-OH; Fmoc-L-Homoserine(O-iPr); (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-4-(propan-2-yloxy)butanoic acid; Fmoc-Hse(OiPr)-OH; N-α-Fmoc-O-isopropyl-L-homoserine
EINECS	Contact for details

Quality Control

Our Fmoc-o-Isopropyl-L-Homoserine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.