Description

2-Quinolinebutanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)- is a sophisticated, non-natural amino acid derivative featuring a quinoline moiety and an Fmoc-protected amine group. This compound is a critical building block in advanced organic synthesis, particularly for the development of novel pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide mimetics, medicinal chemistry, and the discovery of new therapeutic agents. The CAS number for this compound is 2349564-83-4.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially those targeting specific protein interactions.
• Peptidomimetic Synthesis: Used to incorporate the quinoline scaffold into peptide chains, creating analogs with enhanced stability, bioavailability, or receptor affinity.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing compound libraries in high-throughput screening for biological activity.
• Chemical Biology Probes: Employed in the synthesis of labeled or tagged molecules for studying biological pathways and mechanisms.
• Advanced Material Science: Potential precursor for functionalized organic molecules used in specialty polymers or coatings.

Basic Information

Product Name	2-Quinolinebutanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)-
CAS No.	2349564-83-4
Molecular Formula	C₂₈H₂₄N₂O₄
Molecular Weight	452.50 g/mol
Synonyms	(αS)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-quinolinebutanoic acid; Fmoc-(S)-2-quinolylalanine; Fmoc-2-Quin-Ala-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-2-quinolylalanine; Nα-Fmoc-L-2-quinolylalanine; (S)-2-(Fmoc-amino)-3-(quinolin-2-yl)propanoic acid; 2-Quinolinebutanoic acid, α-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (αS)-
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as chiral purity, chemical identity, and assay. We support our clients' regulatory needs with comprehensive documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.