Description

(2S)-2-{((9H-Fluoren-9-Ylmethoxy)Carbonyl)Amino}-4-(2,2,2-Tr CAS NO 2349544-98-3 is a specialized Fmoc-protected amino acid derivative, a critical building block in modern peptide synthesis. Its primary value lies in enabling the precise, automated assembly of complex peptides and peptidomimetics with high fidelity and yield. This compound is essential for researchers and manufacturers in pharmaceutical development, biotechnology, and academic research focused on creating novel therapeutic agents, diagnostic tools, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential addition of amino acids using Fmoc-chemistry protocols.
• Pharmaceutical R&D: Synthesis of peptide-based drug candidates for oncology, metabolic diseases, and central nervous system disorders.
• Peptidomimetic Design: Construction of modified peptide backbones with enhanced stability, bioavailability, and target specificity.
• Combinatorial Chemistry Libraries: Generation of diverse peptide libraries for high-throughput screening against biological targets.
• Bioconjugation: Used in the preparation of peptide-protein or peptide-small molecule conjugates for targeted drug delivery.
• Academic & Institutional Research: Fundamental studies in peptide structure, function, and molecular recognition.

Basic Information

Product Name	(2S)-2-{((9H-Fluoren-9-Ylmethoxy)Carbonyl)Amino}-4-(2,2,2-Tr CAS NO 2349544-98-3
CAS No.	2349544-98-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fmoc-(S)-2-amino-4-(2,2,2-trifluoroethoxy)butanoic acid; Fmoc-L-4-(2,2,2-Trifluoroethoxy)homoalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-4-(2,2,2-trifluoroethoxy)homoalanine; (2S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(2,2,2-trifluoroethoxy)butanoic acid; Fmoc-Homoserine(Tfe)-OH; Fmoc-Hse(Tfe)-OH; Fmoc-L-4-(2,2,2-Trifluoroethoxy)homoserine; A protected non-natural amino acid derivative.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical applications. Quality is verified through multiple analytical techniques including HPLC, NMR, and mass spectrometry to guarantee high chemical purity and correct stereochemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to a cGMP-compliant quality management system to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.