Description

Cyclohexanepentanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αr)- is a specialized, high-purity Fmoc-protected amino acid derivative, a critical building block in modern peptide synthesis. This compound is essential for researchers and manufacturers requiring precise stereochemical control and high coupling efficiency in solid-phase peptide synthesis (SPPS). It is primarily utilized by the pharmaceutical, biotechnology, and advanced materials sectors for the development of novel therapeutic peptides, peptidomimetics, and bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential assembly of complex peptides with defined chirality.
• Pharmaceutical Research & Development: Used in the discovery and production of peptide-based drugs, including hormones, enzyme inhibitors, and targeted therapeutics.
• Peptidomimetic Design: Serves as a scaffold for creating non-natural peptide analogs with enhanced stability, bioavailability, and biological activity.
• Combinatorial Chemistry Libraries: Employed to generate diverse arrays of peptide compounds for high-throughput screening against biological targets.
• Bioconjugation and Labeling: The reactive carboxylic acid group allows for conjugation to other molecules, carriers, or fluorescent tags.
• Academic and Industrial Research: A fundamental reagent for studies in medicinal chemistry, chemical biology, and protein engineering.

Basic Information

Product Name	Cyclohexanepentanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αr)-
CAS No.	2349497-68-1
Molecular Formula	C26H31NO4
Molecular Weight	421.53 g/mol
Synonyms	Fmoc-(R)-2-Amino-2-cyclohexylpentanoic acid; Fmoc-(R)-Amino(cyclohexyl)butyric acid; (2R)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-cyclohexylpentanoic acid; Fmoc-(R)-Cha-OH (where Cha = cyclohexylalanine derivative); N-α-Fmoc-(R)-2-Amino-2-cyclohexylpentanoic acid; Fmoc-(R)-2-Cyclohexyl-2-aminopentanoic acid; Fmoc-protected non-proteinogenic amino acid derivative
EINECS	Contact for details

Quality Control

Our Cyclohexanepentanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αr)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the exacting standards required for peptide synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment to guarantee reproducible performance and supply chain reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to maintain stability and prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.