Description

Benzenepentanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-4-Hydroxy-, (αs)- is a sophisticated, high-purity chemical building block designed for advanced research and synthesis. This compound matters for its role as a key protected amino acid derivative, essential for constructing complex peptides and other bioactive molecules with precise stereochemistry. It is primarily needed by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on drug discovery, proteomics, and the development of novel therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a crucial Fmoc-protected amino acid building block for the automated synthesis of peptides and peptidomimetics.
• Pharmaceutical Intermediate: Used in the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and metabolic disease research.
• Bioconjugation & Probe Development: Acts as a precursor for creating fluorescent probes, affinity labels, and other tools for biochemical and diagnostic applications.
• Combinatorial Chemistry: Employed in the generation of diverse chemical libraries for high-throughput screening in drug discovery programs.
• Academic & Institutional Research: Utilized in university and government labs for fundamental studies in organic chemistry, biochemistry, and medicinal chemistry.
• Custom Synthesis Services: Supplied to contract research and manufacturing organizations (CROs/CMOs) for client-specific custom synthesis projects.

Basic Information

Item	Details
Product Name	Benzenepentanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-4-Hydroxy-, (αs)-
CAS No.	2349331-35-5
Molecular Formula	C26H25NO6
Molecular Weight	447.48 g/mol
Synonyms	Fmoc-4-hydroxy-L-homophenylalanine; Fmoc-Hph(4-OH)-OH; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-4-(4-hydroxyphenyl)butanoic acid; N-α-Fmoc-4-hydroxy-L-homophenylalanine; Fmoc-L-4-hydroxyphenylhomophenylalanine; Fmoc-Hph(p-OH)-OH; Fmoc-4-hydroxy-L-homoPhe-OH; Protected 4-hydroxy-L-homophenylalanine derivative
EINECS	Contact for details

Quality Control

Our Benzenepentanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-4-Hydroxy-, (αs)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with research-grade standards. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and support your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.