Description

1-Cyclohexene-1-Propanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)- is a specialized Fmoc-protected amino acid derivative, a critical building block in modern peptide synthesis. Its value lies in enabling the precise, sequential construction of complex peptides and peptidomimetics under solid-phase conditions. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical development, biotechnology, and advanced materials science who require reliable, high-quality reagents for their synthetic workflows.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid component for the automated synthesis of custom peptides.
• Pharmaceutical Research & Development: Used in the discovery and production of novel peptide-based therapeutics, including hormone analogs and enzyme inhibitors.
• Bioconjugation: Serves as a linker or modified amino acid for creating peptide-protein or peptide-small molecule conjugates.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify bioactive peptide leads.
• Peptidomimetic Design: Integral for synthesizing non-natural peptide analogs with enhanced stability or biological activity.
• Academic & Industrial Research: A fundamental reagent for studies in biochemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	1-Cyclohexene-1-Propanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)-
CAS No.	2348299-84-1
Molecular Formula	C24H25NO4
Molecular Weight	391.46 g/mol
Synonyms	Fmoc-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic acid (Fmoc-Tic-OH); (αS)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-1-cyclohexene-1-propanoic acid; Fmoc-Tic; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid; Fmoc-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid; Fmoc-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (common misnomer); Fmoc-protected Tic amino acid; Nα-Fmoc-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Cyclohexene-1-Propanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)- is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive research and development applications. All materials undergo rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This compound is hygroscopic (moisture-sensitive); containers should be allowed to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.