Description

7H-Pyrrolo[2,3-D]Pyrimidine, 2,5-Dichloro- (CAS NO 2347374-92-7) is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where precise molecular modification is required. Its primary application is as a key synthetic intermediate in the pharmaceutical industry, particularly for the development of kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive heterocyclic structure.
• Chemical Biology: Employed as a molecular probe or precursor in the study of enzyme mechanisms and biological pathways.
• Material Science: Acts as a precursor for the synthesis of specialized organic electronic materials and ligands for catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring functionalized pyrrolopyrimidine cores.
• Academic & R&D: Essential for medicinal chemistry programs in academic and industrial research laboratories exploring new chemical entities.

Basic Information

Product Name	7H-Pyrrolo[2,3-D]Pyrimidine, 2,5-Dichloro-
CAS No.	2347374-92-7
Molecular Formula	C6H3Cl2N3
Molecular Weight	188.02 g/mol
Synonyms	2,5-Dichloro-7H-pyrrolo[2,3-d]pyrimidine; 2,5-Dichloro-7H-pyrrolo[2,3-d]pyrimidine; 2,5-Dichloro-7H-pyrrolo[2,3-d]pyrimidine; 2,5-Dichloro-7H-pyrrolo[2,3-d]pyrimidine; 2,5-Dichloropyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 2,5-dichloro-; 2347374-92-7
EINECS	Contact for details

Quality Control

Our 7H-Pyrrolo[2,3-D]Pyrimidine, 2,5-Dichloro- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.