Description

(Arg)9 Tfa is a high-purity, nonapeptide derivative where the arginine side chains are protected with trifluoroacetyl (Tfa) groups. This compound is a critical intermediate in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptides with multiple arginine residues. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing therapeutic peptides, diagnostic tools, and advanced biomaterials.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a protected building block for the sequential assembly of peptides containing multiple arginine units.
• Therapeutic Peptide Development: Intermediate in the production of cationic cell-penetrating peptides (CPPs), antimicrobial peptides (AMPs), and other bioactive sequences.
• Research & Development: Used in academic and industrial R&D for studying peptide structure-activity relationships (SAR) and developing novel peptide-based drugs.
• Bioconjugation & Labeling: Serves as a precursor for creating labeled peptides for diagnostic imaging or targeted drug delivery systems.
• GMP Manufacturing: Suitable as a starting material in Good Manufacturing Practice (GMP) environments for the production of clinical-grade peptide APIs.

Basic Information

Item	Details
Product Name	(Arg)9 Tfa
CAS No.	2283335-13-5
Molecular Formula	C63H108F27N36O18
Molecular Weight	Contact for details
Synonyms	Nonarginine Trifluoroacetate Salt; Nona-L-arginine TFA Salt; Polyarginine (9) Tfa; Fmoc-Arg(Pbf)-OH (9-mer); L-Arginine nonamer TFA salt; Peptide Synthesis Building Block R9; CPP (9) Tfa Intermediate; Protected Polyarginine
EINECS	Contact for details

Quality Control

Every batch of (Arg)9 Tfa is produced and tested under a rigorous quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting your regulatory and research requirements. A Certificate of Analysis (COA) detailing purity by HPLC, MS confirmation, and other critical parameters is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, freezer environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (Amino Acid Analysis)	≥ 90%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.