Description

Pyrazolo[1,5-A]Pyrimidine-3-Carboxamide, n-[(1R,2R)-2-Methoxycyclobutyl]-7-(Methylamino)-5-[(2-Oxo[1(2H),2'-Bipyridin]-3-Yl)Amino]- is a sophisticated, high-purity chemical intermediate characterized by its complex heterocyclic structure. This compound matters as a critical building block in modern pharmaceutical research, enabling the synthesis of targeted therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on novel small-molecule drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) for targeted therapies.
• Kinase Inhibitor Research: Used in the discovery and development of potent and selective kinase inhibitors due to its privileged scaffold.
• Oncology Drug Development: A valuable building block for constructing novel compounds aimed at cancer treatment pathways.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies and lead optimization campaigns in drug discovery.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial-scale manufacturing of complex drug molecules.
• Biochemical Research: Used as a tool compound or probe to study specific biological mechanisms and protein interactions.

Basic Information

Product Name	Pyrazolo[1,5-A]Pyrimidine-3-Carboxamide, n-[(1R,2R)-2-Methoxycyclobutyl]-7-(Methylamino)-5-[(2-Oxo[1(2H),2'-Bipyridin]-3-Yl)Amino]-
CAS No.	2272904-53-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-[(1R,2R)-2-Methoxycyclobutyl]-7-(methylamino)-5-[(2-oxo-1,2-dihydro-[2,2'-bipyridin]-3-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide; (1R,2R)-N-(2-Methoxycyclobutyl)-7-(methylamino)-5-((2-oxo-1,2-dihydro-[2,2'-bipyridin]-3-yl)amino)pyrazolo[1,5-a]pyrimidine-3-carboxamide; 2272904-53-5; Pyrazolo[1,5-a]pyrimidine-3-carboxamide derivative; Bicyclic heterocyclic carboxamide intermediate
EINECS	Contact for details

Quality Control

Our Pyrazolo[1,5-A]Pyrimidine-3-Carboxamide intermediate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). This material is likely light-sensitive and should be handled under inert atmosphere if found to be easily oxidized. For long-term storage, consider storing under an inert gas such as argon or nitrogen.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Single Unknown Impurity	≤ 1.0%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.