Description

Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid, 5-Chloro-7-(Methylamino)-, Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyrazolopyrimidine core structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and antiviral drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small-molecule drugs targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Oncology Drug Development: Employed in the synthesis of potential kinase inhibitors and other targeted cancer therapies due to its privileged heterocyclic structure.
• Antiviral Agent Synthesis: Serves as a starting material for creating compounds with potential activity against viral enzymes and replication mechanisms.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid, 5-Chloro-7-(Methylamino)-, Ethyl Ester
CAS No.	2271470-64-3
Molecular Formula	C11H11ClN4O2
Molecular Weight	266.68 g/mol
Synonyms	5-Chloro-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester; Ethyl 5-chloro-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxylate; 5-Chloro-7-methylaminopyrazolo[1,5-a]pyrimidine-3-carboxylic Acid Ethyl Ester; CAS 2271470-64-3; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 5-chloro-7-(methylamino)-, ethyl ester; 2271470-64-3
EINECS	Contact for details

Quality Control

Our Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid, 5-Chloro-7-(Methylamino)-, Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.