Description

Pomalidomide-Peg2-N3 is a bifunctional chemical linker designed for advanced bioconjugation and targeted drug delivery applications. This compound is critical for researchers and developers creating next-generation antibody-drug conjugates (ADCs) and other targeted therapeutics. It is primarily utilized by pharmaceutical R&D teams, biotech companies, and academic institutions focused on oncology and immunology.

Application

• Antibody-Drug Conjugate (ADC) Development: Serves as a key linker-payload component, connecting cytotoxic agents to monoclonal antibodies via click chemistry.
• Targeted Cancer Therapy Research: Enables the precise delivery of pomalidomide-based immunomodulatory drugs to specific tumor cells.
• PROTAC (Proteolysis Targeting Chimera) Synthesis: Used as a building block in the construction of heterobifunctional molecules for targeted protein degradation.
• Bioconjugation and Labeling: Facilitates the site-specific attachment of probes, dyes, or other molecules to proteins and peptides for diagnostic and research purposes.
• Chemical Biology Tool Development: Acts as a versatile reagent for studying protein-protein interactions and cellular signaling pathways.
• Precision Medicine Platforms: Integral to the development of novel therapeutic platforms that combine targeting, imaging, and treatment modalities.

Basic Information

Product Name	Pomalidomide-Peg2-N3
CAS No.	2267306-14-7
Molecular Formula	C24H30N6O8
Molecular Weight	530.54 g/mol
Synonyms	Pomalidomide-PEG2-Azide; 4-Azidobutanoic acid-(PEG)2-Pomalidomide ester; 3-(4-Azidobutoxy)-3-oxopropyl 2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindoline-4-carboxylate; Pomalidomide-PEG2-N3; CC-4047-PEG2-Azide; Pomalidomide Azide PEG2 Linker; Pomalidomide-(PEG)2-N3; Pomalidomide-PEG2-Azide
EINECS	Contact for details

Quality Control

Our Pomalidomide-Peg2-N3 is manufactured under strict quality systems to ensure batch-to-batch consistency for critical research and development. Each lot undergoes comprehensive analytical characterization, including HPLC purity analysis, mass spectrometry (MS) for identity confirmation, and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications and test results are provided to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, inert atmosphere. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.