Description

Fmoc-Mehph(4-Cl)-Oh CAS NO 2255321-20-9 is a specialized, non-natural amino acid derivative featuring an Fmoc-protected α-amino group and a 4-chlorophenyl side chain. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the precise incorporation of modified aromatic residues to modulate peptide properties. It is essential for researchers and manufacturers in pharmaceutical development, agrochemical research, and advanced material science who require high-purity, structurally defined intermediates for creating novel bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the automated synthesis of complex peptides and peptidomimetics.
• Pharmaceutical Research & Development: Used to create peptide-based drug candidates, hormone analogs, and diagnostic agents with enhanced stability or binding affinity.
• Agrochemical Innovation: Serves as a precursor in the synthesis of novel bioactive peptides for crop protection and pest management solutions.
• Bioconjugation & Probe Development: Facilitates the site-specific labeling and functionalization of peptides for imaging, targeting, and diagnostic applications.
• Material Science: Employed in the design and synthesis of peptide-based polymers, hydrogels, and surface coatings with tailored properties.
• Academic & Contract Research: A vital reagent for universities and CROs exploring protein-protein interactions, enzyme substrates, and new synthetic methodologies.

Basic Information

Product Name	Fmoc-Mehph(4-Cl)-Oh
CAS No.	2255321-20-9
Molecular Formula	C22H18ClNO4
Molecular Weight	395.84 g/mol
Synonyms	Fmoc-4-chloro-DL-phenylglycine; Fmoc-(4-Cl)Phg-OH; N-(9-Fluorenylmethoxycarbonyl)-4-chlorophenylglycine; (±)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-(4-chlorophenyl)acetic acid; Fmoc-4-Cl-Phg-OH; Fmoc-para-chlorophenylglycine; N-Fmoc-4-chloro-α-phenylglycine
EINECS	Contact for details

Quality Control

Our Fmoc-Mehph(4-Cl)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed under inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.