Description

1-Cyclopropyl-8-Ethoxy-6-Fluoro-7-((4As,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid Hydrochloride is a high-purity, complex fluoroquinolone derivative designed for advanced pharmaceutical research and development. This compound serves as a critical pharmaceutical intermediate or active pharmaceutical ingredient (API) precursor, offering researchers a reliable building block for novel therapeutic agents. It is primarily utilized by R&D teams and manufacturers in the pharmaceutical and biotechnology sectors focusing on the development of next-generation antibacterial agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of novel fluoroquinolone-based Active Pharmaceutical Ingredients (APIs).
• Antibacterial Drug Research: Serves as a core structural scaffold in medicinal chemistry programs aimed at discovering new antibacterial agents with improved efficacy and spectrum.
• Biochemical Research: Used in in vitro studies to investigate structure-activity relationships (SAR) and mechanisms of action against bacterial targets like DNA gyrase and topoisomerase IV.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Process Chemistry Development: Utilized for scaling up and optimizing synthetic routes for complex quinolone derivatives in pilot and commercial manufacturing.

Basic Information

Product Name	1-Cyclopropyl-8-Ethoxy-6-Fluoro-7-((4As,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid Hydrochloride
CAS No.	2252446-70-9
Molecular Formula	C22H26FN3O4 • HCl
Molecular Weight	451.92 g/mol (Free base: 415.46 g/mol)
Synonyms	1-Cyclopropyl-8-ethoxy-6-fluoro-7-((4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride; (4aR,7aR)-6-(1-Cyclopropyl-8-ethoxy-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate-7-yl)octahydro-1H-pyrrolo[3,4-b]pyridine hydrochloride; Fluoroquinolone Derivative CAS 2252446-70-9; Quinolone Carboxylic Acid Hydrochloride Derivative; 7-((4aR,7aR)-Octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-1-cyclopropyl-8-ethoxy-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid HCl; Advanced Fluoroquinolone Intermediate
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-8-Ethoxy-6-Fluoro-7-((4As,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and identity, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods (HPLC, NMR, MS) is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.