Description

1-Cyclopropyl-6,8-Dimethoxy-7-((4As,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel quinolone and fluoroquinolone antibiotic candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• API Development: Serves as a critical precursor in the multi-step synthesis of complex target molecules for preclinical and clinical trials.
• Biochemical Tool Compound: Potential use in biochemical assays to study bacterial enzyme inhibition (e.g., DNA gyrase, topoisomerase IV).
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-Cyclopropyl-6,8-Dimethoxy-7-((4As,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid
CAS No.	2252446-68-5
Molecular Formula	C22H27N3O5
Molecular Weight	413.47 g/mol
Synonyms	1-Cyclopropyl-6,8-dimethoxy-7-(octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; (4As,7As)-1-Cyclopropyl-6,8-dimethoxy-7-(octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; Quinolone Carboxylic Acid Derivative; Octahydropyrrolopyridine-Quinolone Intermediate; CAS 2252446-68-5
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-6,8-Dimethoxy-7-((4As,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.