Description

Ethyl 4-((3,5-Dichloro-4-Methoxybenzyl)Amino)-2-(Methylthio)Pyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) focused on developing new drugs in areas such as oncology and virology.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step production of novel Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Serves as a crucial building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Manufacturing: Used by CDMOs (Contract Development and Manufacturing Organizations) for the scalable synthesis of target molecules under cGMP conditions.
• Oncological Drug Development: Investigated as a core structure in the synthesis of potential kinase inhibitors and other targeted cancer therapies.
• Antiviral Agent Synthesis: Employed in the research and development of new antiviral compounds.
• Chemical Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in pharmaceutical labs.

Basic Information

Product Name	Ethyl 4-((3,5-Dichloro-4-Methoxybenzyl)Amino)-2-(Methylthio)Pyrimidine-5-Carboxylate
CAS No.	2250242-48-7
Molecular Formula	C16H17Cl2N3O3S
Molecular Weight	402.29 g/mol
Synonyms	4-[(3,5-Dichloro-4-methoxybenzyl)amino]-2-(methylsulfanyl)pyrimidine-5-carboxylic acid ethyl ester; Ethyl 4-[(3,5-dichloro-4-methoxybenzyl)amino]-2-(methylthio)-5-pyrimidinecarboxylate; 2-(Methylthio)-4-((3,5-dichloro-4-methoxybenzyl)amino)pyrimidine-5-carboxylic acid ethyl ester; CAS 2250242-48-7; 4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-((3,5-Dichloro-4-Methoxybenzyl)Amino)-2-(Methylthio)Pyrimidine-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.