Description

(2-Chloro-3-Fluoro-4-Iodophenyl)Methanamine is a high-purity, multi-halogenated benzylamine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it a valuable scaffold for developing novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific steric and electronic properties into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used as a building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of advanced polymers and liquid crystals where halogenated aromatic amines modify material properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital intermediate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(2-Chloro-3-Fluoro-4-Iodophenyl)Methanamine
CAS No.	2246363-11-9
Molecular Formula	C7H6ClFIN
Molecular Weight	285.48 g/mol
Synonyms	1-(2-Chloro-3-fluoro-4-iodophenyl)methanamine; (2-Chloro-3-fluoro-4-iodobenzyl)amine; 2-Chloro-3-fluoro-4-iodobenzylamine; 4-Iodo-2-chloro-3-fluorobenzylamine; α-Amino-2-chloro-3-fluoro-4-iodotoluene; Benzenemethanamine, 2-chloro-3-fluoro-4-iodo-
EINECS	Contact for details

Quality Control

Our (2-Chloro-3-Fluoro-4-Iodophenyl)Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP standards where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.