Description

Tau Peptide (472-487)-Peg6-(507-526) (Human) Trifluoroacetate Salt is a synthetic peptide fragment derived from the human microtubule-associated protein tau, incorporating a polyethylene glycol (PEG6) spacer to link two specific regions of the tau sequence. This compound is a critical research-grade biochemical tool for investigating tau protein aggregation, misfolding, and related neurodegenerative pathologies. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic developers focused on Alzheimer's disease and other tauopathies.

Application

• Biochemical Research: Fundamental studies on tau protein structure, function, and aggregation mechanisms.
• Drug Discovery & Screening: Serving as a target or reagent in high-throughput assays to identify potential therapeutic compounds that inhibit tau aggregation.
• Antibody Development & Epitope Mapping: Used to generate and characterize antibodies specific to tau protein regions for diagnostic and therapeutic applications.
• Neurodegenerative Disease Modeling: In vitro studies to model the pathological processes of Alzheimer's disease, frontotemporal dementia, and other tauopathies.
• Diagnostic Assay Development: A key component in the development of ELISA, Western blot, or other immunoassays for detecting tau-related biomarkers.
• Peptide-Based Vaccine Research: Investigated as a potential antigen in vaccine strategies aimed at eliciting an immune response against pathological tau.

Basic Information

Product Name	Tau Peptide (472-487)-Peg6-(507-526) (Human) Trifluoroacetate Salt
CAS No.	2243219-84-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Tau (472-487)-PEG6-(507-526) (human); Human Tau Peptide Fragment (472-487)-PEG6-(507-526) TFA salt; PEGylated Tau Peptide; Tau Aggregation Peptide; Microtubule-associated protein tau fragment; Tau-PEG6 Conjugate; CAS 2243219-84-1
EINECS	Contact for details

Quality Control

Our Tau Peptide (472-487)-Peg6-(507-526) (Human) Trifluoroacetate Salt is produced under stringent conditions to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including mass spectrometry (MS) for sequence confirmation and purity assessment by reversed-phase HPLC. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.